Last update
4/9/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.6
Supplement Facts
Serving Size: 1 Fish Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Cholesterol
<5 mg
1%
Vitamin D3 (as Cholecalciferol) (from Lanolin)
25 mcg (1,000 IU)
125%
Fish Oil Concentrate
1.2 g (1,200 mg)
†
Omega-3 Fatty Acids:
Eicosapentaenoic Acid (EPA)
600 mg
†
Docosahexaenoic Acid (DHA)
300 mg
†
Top Medical Research Studies
9.5
We analyzed the effects of fish oil lipid emulsion on the prevention of deep vein thrombosis in children with intestinal failure.
In this study, we compared 35 pediatric patients receiving a soy oil lipid emulsion with 35 who received fish oil.
Remarkably, none of the children in the fish oil group experienced blood clots, whereas the soy oil group had ten cases. This suggests that fish oil lipid emulsion may significantly reduce the risk of clots associated with central venous catheters.
In this study, we compared 35 pediatric patients receiving a soy oil lipid emulsion with 35 who received fish oil.
Remarkably, none of the children in the fish oil group experienced blood clots, whereas the soy oil group had ten cases. This suggests that fish oil lipid emulsion may significantly reduce the risk of clots associated with central venous catheters.
Read More
9
Omega-3 reduces clot risk post-surgery
We explored the impact of omega-3 fatty acids on blood clot risks in elderly patients recovering from proximal femoral fractures after surgery. In a randomized, double-blind study involving 452 participants, those who received daily supplementation of 1000 mg of omega-3 for 30 days experienced significant reductions in pulmonary embolism and symptomatic deep vein thrombosis compared to those on a placebo. Importantly, these benefits came without an increased risk of bleeding complications.
Read More
9
We investigated the impact of FJH-KO, a source of omega-3 fatty acids from Antarctic krill, on thrombosis in a mouse model. By inducing thrombosis using carrageenan, we treated the mice with FJH-KO beforehand.
The results showed that FJH-KO reduced thrombus formation and prolonged bleeding time. It also lowered levels of substances associated with clotting while boosting protective factors. Additionally, in human cells, FJH-KO inhibited the adhesion of immune cells, suggesting its potential as an antithrombotic agent.
The results showed that FJH-KO reduced thrombus formation and prolonged bleeding time. It also lowered levels of substances associated with clotting while boosting protective factors. Additionally, in human cells, FJH-KO inhibited the adhesion of immune cells, suggesting its potential as an antithrombotic agent.
Read More
Most Useful Reviews
9
Lowered triglyceride levels
2 people found this helpful
I take omega-3s to reduce blood triglyceride levels. After a couple of months, I experienced a threefold decrease—an excellent result. I intend to continue. The golden transparent capsules are large but swallowable. I take two before bed, along with vitamin D.
Read More
6
Good for skin.
210 people found this helpful
Get your necessary Omega-3s with just 1-2 capsules daily. This dietary supplement contributes to good skin and hair condition, cardiovascular support, and metabolic process normalisation. It also stimulates the immune system and improves blood properties. The capsules are large yet easy to swallow, and there's no aftertaste.
Read More
7.5
Elimination of tinnitus
2 people found this helpful
Vitamin D levels improved from 13 (deficient) to 26 in a month of usage. This supplement was purchased, mainly to enhance vitamin D absorption, without high hopes for fatty acids. Unwanted tinnitus, which lasted seconds, ceased after three weeks, suggesting a beneficial effect on blood vessels (I am a doctor and can draw such conclusions). I’ve made no lifestyle changes. Skin colour improved and nails are less brittle, although that remains uncertain.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
- All Researches
9.5
We analyzed the effects of fish oil lipid emulsion on the prevention of deep vein thrombosis in children with intestinal failure.
In this study, we compared 35 pediatric patients receiving a soy oil lipid emulsion with 35 who received fish oil.
Remarkably, none of the children in the fish oil group experienced blood clots, whereas the soy oil group had ten cases. This suggests that fish oil lipid emulsion may significantly reduce the risk of clots associated with central venous catheters.
In this study, we compared 35 pediatric patients receiving a soy oil lipid emulsion with 35 who received fish oil.
Remarkably, none of the children in the fish oil group experienced blood clots, whereas the soy oil group had ten cases. This suggests that fish oil lipid emulsion may significantly reduce the risk of clots associated with central venous catheters.
Read More
9
We investigated the impact of FJH-KO, a source of omega-3 fatty acids from Antarctic krill, on thrombosis in a mouse model. By inducing thrombosis using carrageenan, we treated the mice with FJH-KO beforehand.
The results showed that FJH-KO reduced thrombus formation and prolonged bleeding time. It also lowered levels of substances associated with clotting while boosting protective factors. Additionally, in human cells, FJH-KO inhibited the adhesion of immune cells, suggesting its potential as an antithrombotic agent.
The results showed that FJH-KO reduced thrombus formation and prolonged bleeding time. It also lowered levels of substances associated with clotting while boosting protective factors. Additionally, in human cells, FJH-KO inhibited the adhesion of immune cells, suggesting its potential as an antithrombotic agent.
Read More
9
We investigated how docosahexaenoic acid (DHA) and its derivatives affect platelet activity and blood clotting. Our findings revealed that DHA, along with its oxidized forms, effectively reduced platelet aggregation and activation, particularly in mouse models.
Although DHA showed some benefits, the most significant effects on blood clots came from its oxylipins, specifically 11-HDHA and 14-HDHA. These compounds appeared to inhibit platelet adhesion and thrombus formation through a specific signaling pathway, enhancing the potential for DHA as a treatment for clot-related cardiovascular issues.
Although DHA showed some benefits, the most significant effects on blood clots came from its oxylipins, specifically 11-HDHA and 14-HDHA. These compounds appeared to inhibit platelet adhesion and thrombus formation through a specific signaling pathway, enhancing the potential for DHA as a treatment for clot-related cardiovascular issues.
Read More
9
Omega-3 reduces clot risk post-surgery
We explored the impact of omega-3 fatty acids on blood clot risks in elderly patients recovering from proximal femoral fractures after surgery. In a randomized, double-blind study involving 452 participants, those who received daily supplementation of 1000 mg of omega-3 for 30 days experienced significant reductions in pulmonary embolism and symptomatic deep vein thrombosis compared to those on a placebo. Importantly, these benefits came without an increased risk of bleeding complications.
Read More
We examined how fish oil, rich in omega-3 polyunsaturated fatty acids (PUFAs), impacts blood clotting in individuals at moderate risk for cardiovascular diseases. In a controlled study with 40 participants, we discovered that fish oil supplementation led to significant changes in circulating extracellular vesicles (EVs), which are linked to clotting processes.
Notably, the fish oil reduced the coagulatory activity of these EVs, suggesting a protective effect against thrombus formation. This finding opens up new avenues for preventing blood clots and managing cardiovascular health.
Notably, the fish oil reduced the coagulatory activity of these EVs, suggesting a protective effect against thrombus formation. This finding opens up new avenues for preventing blood clots and managing cardiovascular health.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Lowered triglyceride levels
2 people found this helpful
I take omega-3s to reduce blood triglyceride levels. After a couple of months, I experienced a threefold decrease—an excellent result. I intend to continue. The golden transparent capsules are large but swallowable. I take two before bed, along with vitamin D.
Read More
6
Good for skin.
210 people found this helpful
Get your necessary Omega-3s with just 1-2 capsules daily. This dietary supplement contributes to good skin and hair condition, cardiovascular support, and metabolic process normalisation. It also stimulates the immune system and improves blood properties. The capsules are large yet easy to swallow, and there's no aftertaste.
Read More
7.5
Elimination of tinnitus
2 people found this helpful
Vitamin D levels improved from 13 (deficient) to 26 in a month of usage. This supplement was purchased, mainly to enhance vitamin D absorption, without high hopes for fatty acids. Unwanted tinnitus, which lasted seconds, ceased after three weeks, suggesting a beneficial effect on blood vessels (I am a doctor and can draw such conclusions). I’ve made no lifestyle changes. Skin colour improved and nails are less brittle, although that remains uncertain.
Read More
9
Supports blood vessels.
1 people found this helpful
Omega-3 helps maintain blood vessel elasticity and reduces plaque buildup, crucial at my age. It aids in normal blood pressure levels and triglycerides, with excellent anti-inflammatory properties. Despite the capsules being hard to swallow, I drink them during a fatty meal, which enhances absorption. The taste is delightful—slightly lemony.
Read More
7.5
Normalises blood levels.
1 people found this helpful
I've been taking this Ultra Omega-3 with vitamin D3 for over a year. It remarkably improved my health, normalising blood counts and preventing dry skin. Buying a larger jar was economical, and this formula is my favourite for its reliable benefits.
Read More
Frequently Asked Questions
9
Lowered triglyceride levels
2 people found this helpful
I take omega-3s to reduce blood triglyceride levels. After a couple of months, I experienced a threefold decrease—an excellent result. I intend to continue. The golden transparent capsules are large but swallowable. I take two before bed, along with vitamin D.
9
Supports blood vessels.
1 people found this helpful
Omega-3 helps maintain blood vessel elasticity and reduces plaque buildup, crucial at my age. It aids in normal blood pressure levels and triglycerides, with excellent anti-inflammatory properties. Despite the capsules being hard to swallow, I drink them during a fatty meal, which enhances absorption. The taste is delightful—slightly lemony.
We examined how fish oil, rich in omega-3 polyunsaturated fatty acids (PUFAs), impacts blood clotting in individuals at moderate risk for cardiovascular diseases. In a controlled study with 40 participants, we discovered that fish oil supplementation led to significant changes in circulating extracellular vesicles (EVs), which are linked to clotting processes.
Notably, the fish oil reduced the coagulatory activity of these EVs, suggesting a protective effect against thrombus formation. This finding opens up new avenues for preventing blood clots and managing cardiovascular health.
Notably, the fish oil reduced the coagulatory activity of these EVs, suggesting a protective effect against thrombus formation. This finding opens up new avenues for preventing blood clots and managing cardiovascular health.
7
We investigated the link between omega-3 fatty acids and blood clot markers in patients with atrial fibrillation. By analyzing data from over 2,370 participants, we found that higher levels of total omega-3s were connected to lower levels of D-dimer and beta-thromboglobulin, both indicators of activated coagulation and platelet activity.
This suggests that omega-3s may help reduce blood clot risks. However, while some individual fatty acids showed varied effects, the overall trend points to the potential antithrombotic benefits of these healthy fats.
This suggests that omega-3s may help reduce blood clot risks. However, while some individual fatty acids showed varied effects, the overall trend points to the potential antithrombotic benefits of these healthy fats.
9
We investigated the impact of FJH-KO, a source of omega-3 fatty acids from Antarctic krill, on thrombosis in a mouse model. By inducing thrombosis using carrageenan, we treated the mice with FJH-KO beforehand.
The results showed that FJH-KO reduced thrombus formation and prolonged bleeding time. It also lowered levels of substances associated with clotting while boosting protective factors. Additionally, in human cells, FJH-KO inhibited the adhesion of immune cells, suggesting its potential as an antithrombotic agent.
The results showed that FJH-KO reduced thrombus formation and prolonged bleeding time. It also lowered levels of substances associated with clotting while boosting protective factors. Additionally, in human cells, FJH-KO inhibited the adhesion of immune cells, suggesting its potential as an antithrombotic agent.
9
Omega-3 reduces clot risk post-surgery
We explored the impact of omega-3 fatty acids on blood clot risks in elderly patients recovering from proximal femoral fractures after surgery. In a randomized, double-blind study involving 452 participants, those who received daily supplementation of 1000 mg of omega-3 for 30 days experienced significant reductions in pulmonary embolism and symptomatic deep vein thrombosis compared to those on a placebo. Importantly, these benefits came without an increased risk of bleeding complications.
7
Omega-3s reduce thrombin generation
We explored the effects of omega-3 fatty acids, specifically docosahexaenoic acid and eicosapentaenoic acid, on blood clotting functions. Using well-designed models, we found that while these omega-3s didn’t significantly alter many platelet functions, they did slow down thrombin generation, a key factor in blood clot formation.
Interestingly, in mice on an omega-3 enriched diet, we observed reduced platelet accumulation in thrombi. This suggests that omega-3 fish oil may indeed have a protective role in cardiovascular health, particularly in moderating blood clot formation.
Interestingly, in mice on an omega-3 enriched diet, we observed reduced platelet accumulation in thrombi. This suggests that omega-3 fish oil may indeed have a protective role in cardiovascular health, particularly in moderating blood clot formation.
References
- Bozbas E, Zhou R, Soyama S, Allen-Redpath K, Mitchell JL, et al. Dietary n-3 polyunsaturated fatty acids alter the number, fatty acid profile and coagulatory activity of circulating and platelet-derived extracellular vesicles: a randomized, controlled crossover trial. Am J Clin Nutr. 2024;119:1175. 10.1016/j.ajcnut.2024.03.008
- Reiner MF, Bertschi DA, Werlen L, Wiencierz A, Aeschbacher S, et al. Omega-3 Fatty Acids and Markers of Thrombosis in Patients with Atrial Fibrillation. Nutrients. 2024;16. 10.3390/nu16020178
- Lee GH, Lee SY, Chae JY, Kim JW, Kim JH, et al. Antarctic Krill Oil from Ameliorates Carrageenan-Induced Thrombosis in a Mouse Model. Int J Mol Sci. 2023;24. 10.3390/ijms242417440
- Pawelzik SC, Arnardottir H, Sarajlic P, Mahdi A, Vigor C, et al. Decreased oxidative stress and altered urinary oxylipidome by intravenous omega-3 fatty acid emulsion in a randomized controlled trial of older subjects hospitalized for COVID-19. Free Radic Biol Med. 2023;194:308. 10.1016/j.freeradbiomed.2022.12.006
- Yamaguchi A, Stanger L, Freedman CJ, Standley M, Hoang T, et al. DHA 12-LOX-derived oxylipins regulate platelet activation and thrombus formation through a PKA-dependent signaling pathway. J Thromb Haemost. 2021;19:839. 10.1111/jth.15184
- Zheng X, Jia R, Li Y, Liu T, Wang Z. Omega-3 fatty acids reduce post-operative risk of deep vein thrombosis and pulmonary embolism after surgery for elderly patients with proximal femoral fractures: a randomized placebo-controlled, double-blind clinical trial. Int Orthop. 2020;44:2089. 10.1007/s00264-020-04610-0
- Gaertner S, Auger C, Farooq MA, Pollet B, Khemais-Benkhiat S, et al. Oral Intake of EPA:DHA 6:1 by Middle-Aged Rats for One Week Improves Age-Related Endothelial Dysfunction in Both the Femoral Artery and Vein: Role of Cyclooxygenases. Int J Mol Sci. 2020;21. 10.3390/ijms21030920
- Isaksen T, Evensen LH, Brækkan SK, Hansen JB. Dietary Intake of Marine Polyunsaturated n-3 Fatty Acids and Risk of Recurrent Venous Thromboembolism. Thromb Haemost. 2019;119:2053. 10.1055/s-0039-1697663
- Carnevale LN, Das A. Novel Anti-inflammatory and Vasodilatory ω-3 Endocannabinoid Epoxide Regioisomers. Adv Exp Med Biol. 2019;1161:219. 10.1007/978-3-030-21735-8_17
- Skulas-Ray AC, Wilson PWF, Harris WS, Brinton EA, Kris-Etherton PM, et al. Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association. Circulation. 2019;140:e673. 10.1161/CIR.0000000000000709
- Viecelli AK, Polkinghorne KR, Pascoe EM, Paul-Brent PA, Hawley CM, et al. Fish oil and aspirin effects on arteriovenous fistula function: Secondary outcomes of the randomised omega-3 fatty acids (Fish oils) and Aspirin in Vascular access OUtcomes in REnal Disease (FAVOURED) trial. PLoS One. 2019;14:e0213274. 10.1371/journal.pone.0213274
- Akintoye E, Sethi P, Harris WS, Thompson PA, Marchioli R, et al. Fish Oil and Perioperative Bleeding. Circ Cardiovasc Qual Outcomes. 2018;11:e004584. 10.1161/CIRCOUTCOMES.118.004584
- Spector AA, Kim HY. Emergence of omega-3 fatty acids in biomedical research. Prostaglandins Leukot Essent Fatty Acids. 2019;140:47. 10.1016/j.plefa.2018.11.017
- Tam KW, Wu MY, Siddiqui FJ, Chan ES, Zhu Y, et al. Omega-3 fatty acids for dialysis vascular access outcomes in patients with chronic kidney disease. Cochrane Database Syst Rev. 2018;11:CD011353. 10.1002/14651858.CD011353.pub2
- Jami MM, Bhardwaj V, Merritt RJ. Intravenous Fish Oil Lipid Emulsion Prevents Catheter-Related Thromboses in Pediatric Patients with Intestinal Failure. J Pediatr. 2018;198:301. 10.1016/j.jpeds.2018.03.029
- Adili R, Voigt EM, Bormann JL, Foss KN, Hurley LJ, et al. In vivo modeling of docosahexaenoic acid and eicosapentaenoic acid-mediated inhibition of both platelet function and accumulation in arterial thrombi. Platelets. 2019;30:271. 10.1080/09537104.2017.1420154
Data last updated:
